Immunosuppression and transplantation-related characteristics affect the difference between eGFR equations based on creatinine compared to cystatin C in kidney transplant recipients.

High HbA1c (reflecting glycemic control) and repeat transplantation showed a trend toward impacting the difference between eGFRcr and eGFRcys in the logistic regression model.

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Other factors are associated with either smaller or greater differences between eGFRcr and eGFRcys, as demonstrated in Table 3 : Impaired glycemic control (demonstrated with higher HbA1c-values) is independently associated with a greater difference, comparing eGFRcr EKFC 2021 to eGFRcys EKFC 2023 (OR 1.252, 95% CI 1.023–1.531, P = .029) and indicated potential associations in other comparisons, although these did not reach statistical significance (Fig. 5 ).

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