Construction of the miRNA/Pyroptosis-Related Molecular Regulatory Axis in Abdominal Aortic Aneurysm: Evidence From Transcriptome Data Combined With Multiple Machine Learning Approaches Followed by Experiment Validation.

Furthermore, higher PRG scores were observed in males ( p < 0.05, Figure 4 D) and hypertensive patients ( p < 0.01, Figure 4 F), while smokers ( p > 0.05, Figure 4 E) displayed elevated PRG scores that did not reach statistical significance.

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Other clinical indicators, such as diastolic pressure ( Figure 4 G), age (Supporting Information 4 : Figure S1), BMI (Supporting Information 4 : Figure S1), systolic pressure (Supporting Information 5 : Figure S2), cholesterol (Supporting Information 5 : Figure S2), and FBG (Supporting Information 5 : Figure S2), did not yield significant statistical differences, but diastolic pressure showed a significant trend.

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