In Vitro Assessment of the Neuroprotective Effects of Pomegranate (<i>Punica granatum</i> L.) Polyphenols Against Tau Phosphorylation, Neuroinflammation, and Oxidative Stress.

The aril treatments showed a significant trend ( p < 0.05) of attenuating the induced oxidative stress ( Figure 4 B).

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In our experiment, the pomegranate treatments showed a trend of mitigating M1-related neurotoxicity by decreasing the expression of the cell surface receptor CD86 and increasing CD163 protein expression ( Figure 6 ).

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