Low Muscle Mass is Independently Associated with an Increased Risk of Having Lower Limb Atherosclerosis in T2DM Patients.

Although the difference between the two groups did not reach statistical significance (P=0.05), it still reveals a noticeable tendency: statin use is more prevalent among the population of patients with T2DM and lower limb atherosclerosis.

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However, although our data showed a trend of increased levels of TNF-α in patients with lower limb arteriosclerosis compared to those with normal lower limbs, the differences in IL-6 and TNF-α between the two groups were not statistically significant.

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Similar to these findings, our study found that compared to the group without lower extremity arteriosclerosis, the lower extremity arteriosclerosis group had significantly lower total-P1NP and N-MID levels, and β-CTX also showed a decreasing trend, although the difference was not statistically significant.

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