Metformin plus lifestyle interventions versus lifestyle interventions alone for the delay or prevention of type 2 diabetes in individuals with prediabetes: a meta-analysis of randomized controlled trials.

Diabetol Metab Syndr · 2024 · PMC11562588 · PMID 39543645

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did not reach statistical significanceP = 0.11not close (p > 0.1)

showed a trendno p-value reported

Weight Our pooled studies at endpoints showed a trend towards higher weight with lifestyle interventions plus metformin; however, this did not reach statistical significance (SMD = 0.12, 95% CI [-0.03, 0.27], P = 0.11).

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