Serum microRNA qPCR profiling and validation indicate upregulation of circulating miR-145-5p and miR-26a-5p in migraineurs.

A distinct tendency to differentiate these two groups was also observed for miR-126-3p but it did not reach statistical significance (Table 3 ).

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On this basis, we also decided to include miR-424-5p and miR-27b-5p, which both showed a trend towards differential expression that did, however not reach statistical significance ( p = 0.064 and 0.081, respectively).

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