Prognostic characteristics and drug sensitivity analysis of hepatocellular carcinoma based on histone modification-related genes: a multi-omics integrated study revealing potential therapeutic targets and individualized treatment strategies.

Although differences in stromal scores ( Figure 9A , p = 0.074) and immune scores ( Figure 9B , p = 0.053) between high- and low-risk groups did not reach statistical significance, the high-risk group showed a trend towards lower scores in both metrics, suggesting that high-risk HCC may have weaker immune responses and stromal components.

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