Although HIF-1α positivity showed a trend towards poorer survival, the results did not reach statistical significance ( p = 0.07).
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Prognostic Significance of Microvessel Density and Hypoxic Markers in Canine Osteosarcoma: Insights into Angiogenesis and Tumor Aggressiveness.
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a statistical trendp = 0.15
171 days, p = 0.045; Figure 3 B), while only a statistical trend was observed for OS (150 vs. 202 days, p = 0.15; Figure 3 A).
In addition, while the expression of another hypoxia-related protein, HIF-1α, showed a trend towards poorer patient survival, this was not statistically significant.