The Antiviral Effects of Heat-Killed <i>Lactococcus lactis</i> Strain Plasma Against Dengue, Chikungunya, and Zika Viruses in Humans by Upregulating the IFN-α Signaling Pathway.

Microorganisms · 2024 · PMC11596828 · PMID 39597693

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hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

showed a trendp = 0.052so close (0.05 < p ≤ 0.1)

Statistical analysis using the nonparametric Steel test suggested a statistically significant reduction ( p < 0.05) in infectious viral particles for CHIKV and ZIKV, while the anti-DENV effect of LCP Sup 1:10 showed a trend towards reduction ( p = 0.052).

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did not reach statistical significanceno p-value reported

However, the increase in CD86 levels in pDCs following LC-Plasma treatment did not reach statistical significance, despite exhibiting a higher fold change (2.34-fold) compared to HLA-DR (1.39-fold). 3.3.

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