Levamisole Ameliorates Rheumatoid Arthritis by Downregulating the PI3K/Akt Pathway in SD Rats.

In contrast, compared with the Model group, the M-LVM group showed considerable differences in the expression of the p-PI3K ( p < 0.05), PI3K ( p < 0.01), p-Akt ( p < 0.05), and Akt ( p < 0.01) proteins, while these protein expressions in the L-LVM and H-LVM groups did not reach statistical significance.

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LVM Suppressed RA Progress in AIA Rat Model The body weights of the rats in each group showed a trend of smoothly increasing, with no significant differences observed among these groups ( Figure 2 A).

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