Immunity Dynamics of <i>Neisseria meningitidis</i> Serogroups ACYW from Birth and Following Vaccination.

For the unvaccinated participants, the GMC for serogroup A showed a trend of flattening and then decreasing.

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In 2019–2022, Anti-Nm IgG positivity rates for serogroups A and C showed an increasing trend when compared with serogroups Y and W, with a fluctuating trend.

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Since the introduction of meningococcal polysaccharide vaccine group A (MPSV-A) and meningococcal polysaccharide vaccine groups A and C (MPSV-AC) into the immunization plan of China in 2007, the incidence of serogroups A and C showed a decreasing trend year by year in China [ 11 , 12 , 13 ].

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There was a significant trend of increasing antibody positivity as the number of doses increased ( Figure 3 C).

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