Androgen Effects on Alcohol-induced Liver Fibrosis Are Controlled by a Notch-dependent Epigenetic Switch.

Cell Mol Gastroenterol Hepatol · 2025 · PMC11609386 · PMID 39349250

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did not reach statistical significanceno p-value reported

In addition, AAV-CMV-Cre and AAV-GFAP-Cre produced a small decrease in hypothalamus Kdm5b expression that did not reach statistical significance but could possibly affect mouse feeding behavior and thus contribute to the phenotype of KO mice.

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showed a trendno p-value reported

Some of the parameters (ALT, PT, Col1a1 mRNA) showed a trend towards an increase, but the magnitude of the effect was overall small.

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