IL-33-experienced group 2 innate lymphoid cells in the lung are poised to enhance type 2 inflammation selectively in adult female mice.

2 C showed a trend for an increase in the number of IL-25R + ILC2s selectively in females 4 weeks post OVA/IL-33 administration.

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Interestingly, there was also a clear trend for these cells to increase 4 weeks after OVA/IL-33 administration and prior to OVA challenge, again selectively in females.

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