15.4 [1.5]; p = 0.020) ( Figure 3D ), and near-significant elevations in percentages of both CD8 + T cells and naïve CD4 + T cells. 4 Discussion The COVID-19 pandemic is reminiscent of the dilemma in our daily practice, which is to maintain adequate immunosuppression for controlling autoimmune diseases while risking a higher probability of non-responsiveness to vaccination ( 12 , 13 ).
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Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.
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These trends were also noticed in patients receiving their third vaccination, though some did not reach statistical significance.