The evidence from in vitro primary fibroblasts and a randomized, double-blind, placebo-controlled clinical trial of tuna collagen peptides intake on skin health.

In contrast, the TEWL of the placebo group in the face remained consistent, while the forearm showed an increasing trend, as depicted in Figure 4C,D , respectively.

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Nevertheless, the observed difference between the groups did not reach statistical significance. 22 When considering the relative mean change (%) in the TEWL from baseline, the TCP group displayed a trend in reducing TEWL by −2.5% and −10.4% in the face and by −2.7% and −5.8% in the forearm at 4 and 8 weeks, respectively.

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The TCP group showed a trend of increasing the relative mean change (%) in skin hydration from baseline by 12.2% and 30.6% in 4 and 8 weeks, respectively.

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