Barely Significant
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Novel Applicator Utilizing HIFES and Enhanced Synchronized Radiofrequency+ for Subcutaneous Fat Reduction: Porcine Model Study.

Lasers Surg Med · 2024 · PMC11629285 · PMID 39462846

2
hedged sentences
0.9900
closest p · 19.8× alpha
0.9900
boldest claim

The sentences

a clear trendp ‐value > 0.99not close (p > 0.1)
The control group had no significant change or a clear trend in the caspase‐9 (at 1 h −6.12%, at 6 h −2.58%, at 24 h −5.86%, p ‐value > 0.99) or caspase‐3 gene expression (at 1 h after first treatment +6.47%, at 6 h −1.21%, and at 24 h −3.15%, p ‐value 0.96), and bcl2l1 increased in the control group ( p ‐value > 0.99, at 1 h +18.97%, at 6 h +25.72%, at 24 h +10.84%).

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Although the change of bcl2l1 gene expression did not reach statistical significance, compared to the baseline, the changes of the active group showed a hypothesized trend, with increased levels of proapoptotic markers, while the antiapoptotic bcl2l1 mRNA levels decreased.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.