Identifying predictors of treatment response and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-negative breast cancer: the NEOENDO translational study.

21 Similar results were observed after PSM, though PgR reduction did not reach statistical significance in the NACT cohort ( Supplementary Table S5 , available at https://doi.org/10.1016/j.esmoop.2024.103989 ).

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Regarding post-surgical tumor features, although pCR and RCB-0/I per se did not show a significant association with outcomes, a clear trend for better EFS was observed ( Supplementary Figure S4 , available at https://doi.org/10.1016/j.esmoop.2024.103989 ).

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