Altered lipid profile and reduced neuronal support in human induced pluripotent stem cell-derived astrocytes from adrenoleukodystrophy patients.

J Inherit Metab Dis · 2025 · PMC11660744 · PMID 39704488

Europe PMC DOI

hedged sentences

0.1373

closest p · 2.7× alpha

0.1373

boldest claim

The sentences

showed a trendp = 0.1373not close (p > 0.1)

In addition, we observed an increase in ABCD1 abundance in control hiPSC‐derived astrocytes incubated with C26:0, whereas hiPSC‐derived astrocytes incubated with C26:1 showed a trend suggesting a decrease ( p = 0.1373, Figure 3B ).

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did not reach statistical significanceno p-value reported

Although it did not reach statistical significance, on average we observed an increase in presynaptic SYN puncta in the co‐cultures with ALD hiPSC‐derived astrocytes.

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