Human intraepithelial mast cell differentiation and effector function are directed by TGF-β signaling.

J Clin Invest · 2025 · PMC11684804 · PMID 39744949

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did not reach statistical significanceno p-value reported

Expression of IL13 was only detected in the lamina propria, although this did not reach statistical significance ( Supplemental Figure 6G ).

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showed a trendno p-value reported

Transcript encoding integrin β 6 ( ITGB6 ), which pairs with integrin α V to mediate latent TGF-β activation and regulate murine mucosal MC development ( 16 , 17 ), showed a trend toward upregulation in CRSwNP EpC compared with CRSsNP ( Supplemental Figure 4B ).

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