MicroRNAs as potential diagnostic biomarkers for bipolar disorder.

Neural Regen Res · 2025 · PMC11688563 · PMID 39104098

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did not reach statistical significanceno p-value reported

RT-PCR confirmed all the significant differences except for miR-29c-5p which did not reach statistical significance.

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nominally significantno p-value reported

Of the 16 reliably detected miRNAs, 3 (miR-15b, -132, and -652) showed a nominally significant increase in expression in the high-risk subjects compared to the control subjects (miR-15b, FC = 1.29; miR-132, FC = 1.34; miR-652, FC = 1.26).

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on the borderline of significanceno p-value reported

MiR-4286 was significantly increased after Tukey correction in SC compared to both LR and controls in untreated LCLs, while miR-186-5p was significantly decreased in SC compared to LR and on the borderline of significance of being decreased in SC compared to controls in lithium-treated LCLs.

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