Cathepsin C (dipeptidyl peptidase 1) inhibition in adults with bronchiectasis: AIRLEAF, a phase II randomised, double-blind, placebo-controlled, dose-finding study.

Eur Respir J · 2025 · PMC11694546 · PMID 39255990

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did not reach statistical significanceno p-value reported

As this comparison did not reach statistical significance, all following evaluations presented in this manuscript are considered exploratory.

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showed a trendno p-value reported

Results from patient-reported outcomes of quality of life showed a trend in favour of the BI 1291583 2.5 mg and 5 mg doses.

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