However, unlike in single KO mice, the differences in %EF and %FS between Rgs2/5 dbKO and WT mice showed a trend but did not reach statistical significance (Figure 1k, l ).
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Germline deletion of Rgs2 and/or Rgs5 in male mice does not exacerbate left ventricular remodeling induced by subchronic isoproterenol infusion.
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