Effects of aerobic training on brain architecture, hippocampal volume, cardiorespiratory parameters, and health-related quality of life among patients with schizophrenia: A systematic review.

The subjects presented with a 34% increase in STM score after the exercise program, while control subjects with a 17% lower score after exercise.[ 30 ] Association between an increase in right hippocampal volume and improved performance of the Rey Memory Test (rho < 0.23; P < 0.10) was borderline significant.[ 33 ] Resistance programs on functional ability exhibited significant time effects (F (2, 7.791) =32.638; P = .000) in the GAF, with an improvement in scores over time.

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Patients showed significant improvements in maximal achieved power at termination of the test (9% increase, 16 W, P = 0.025), while healthy controls showed a trend toward improvement (6%, 13 W, P = 0.057).[ 27 ] Cognitive function Improvement in short-term memory (STM) scores for combined exercise and nonexercise schizophrenia groups was correlated with change in hippocampal volume (r = 0.51; P < .05).

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In addition, an increase in left hippocampal volume was also associated with an increase in verbal performance of the Buschke selective reminding test.[ 29 ] Based on the CDS, a strong trend for reduced depression was found in a study conducted to determine an increase in the hippocampal plasticity in response to exercise in chronic schizophrenia patients (p. = 0.06).

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