Brain iron deposition and cognitive decline in patients with cerebral small vessel disease : a quantitative susceptibility mapping study.

Alzheimers Res Ther · 2025 · PMC11715900 · PMID 39789638

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a near-significant trendno p-value reported

Additionally, a mediation analysis conducted on age-matched subgroups also indicated a near-significant trend in the mediating role of the CSVD total score between age and striatal iron deposition, further details can be found in Supplementary Table S4 and Fig. 1 .

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did not reach statistical significanceno p-value reported

Although age and diabetes history were found to influence the mean susceptibility values of the thalamus, these effects did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.