Pulmonary artery denervation by noninvasive stereotactic radiotherapy: a pilot study in swine models of pulmonary hypertension.

Nat Commun · 2025 · PMC11718002 · PMID 39788963

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did not reach statistical significanceno p-value reported

In addition, diastolic PAP post-PADN in response to TxA2 infusion showed a similar trend like mean and systolic PAP, but did not reach statistical significance in comparison to the untreated animals (Fig. 2 ).

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showed a trendno p-value reported

Moreover, PADN by 20-Gy SBRT led to more significant reduction in medial wall thickness ( P < 0.05), and showed a trend towards a lower rate of full muscularization than RFA (Fig. 9 ).

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