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CEST imaging combined with <sup>1</sup>H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer's disease mice.

Alzheimers Res Ther · 2025 · PMC11726951 · PMID 39806490

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However, changes in GABACEST signals at 20 week did not reach statistical significance compared to baseline.

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showed a trendno p-value reported
While GABACEST signals showed a trend towards increased GABA levels in riluzole-treated AD mice, particularly in the early stages of treatment.

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