Biologics as well as inhaled anti-asthmatic therapy achieve clinical remission: Evidence from the Severe Asthma Network in Italy (SANI).

World Allergy Organ J · 2025 · PMC11741032 · PMID 39829953

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0630

boldest claim

The sentences

close to significancep = 0.057so close (0.05 < p ≤ 0.1)

The analysis of demographic characteristics of the 2 groups highlights few statistical differences: the Body Surface Area (BSA) significantly differs (p = 0.015), and the Body Mass Index (BMI) is close to significance (p = 0.057) as the absolute eosinophil count (p = 0.050).

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did not reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)

Although this suggests a trend of higher eosinophil counts in patients who did not achieve remission, the difference approached but did not reach statistical significance (p = 0.063).

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showed a trendno p-value reported

Asthma control, as measured by the ACT and ACQ, showed a trend where the no CR group had lower ACT scores (mean 15.9, SD = 4.1) and higher ACQ scores (mean 2.2, SD = 1.2), indicating poorer asthma control compared to the other groups, though these differences were not statistically significant (ACT: p = 0.069; ACQ: p = 0.245).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.