Steroid hormone receptors, exome sequencing and treatment responsiveness of breast cancer patient-derived xenografts originated in a South American country.

Paclitaxel induced a slight decrease in tumor size that did not reach statistical significance and fulvestrant had no inhibitory effect.

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PDX BC-AR685 showed a trend of growing inside the mouse mammary ducts resembling the areas of DCIS observed in the patient (Fig. 4 B).

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