β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.

While there was a trend toward increased expression in advanced stages, particularly for OSM in T4 stage tumors, the correlation with overall pathological staging did not reach statistical significance, possibly due to limited sample sizes ( Fig. 1 C).

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While tumor specimens showed a trend toward increased macrophage infiltration, this variation did not reach statistical significance, likely reflecting inherent inter-patient heterogeneity ( Fig. 2 E).

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