Efficacy analysis of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer: a retrospective study.

Front Oncol · 2024 · PMC11754059 · PMID 39850825

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0880

boldest claim

The sentences

showed a trendp = 0.055so close (0.05 < p ≤ 0.1)

However, in the analysis of DFS ( Figures 3C, D ), the original cohort showed a trend toward improved DFS in the HIPEC group, approaching statistical significance (HR 0.700; 95% CI 0.486–1.010; p = 0.055).

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marginally significantP = 0.055so close (0.05 < p ≤ 0.1)

In our study, the Kaplan-Meier curve before PSM showed higher DFS in the HIPEC group, but the difference was marginally significant ( P = 0.055), likely due to baseline imbalances between the two groups.

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did not reach statistical significancep = 0.088so close (0.05 < p ≤ 0.1)

Regarding recurrence patterns, the original cohort showed that the non-HIPEC group (15.1%) had a greater risk of isolated PM than the HIPEC group (6.9%), but the difference did not reach statistical significance ( p = 0.088).

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