Delayed neutrophil recovery following BCMA CAR-T therapy in Duffy-null myeloma does not impact severe infections or survival.

Duffy-null patients showed a trend toward lower ANC at day 30 (0.9 vs 1.4; P = .07), with significantly lower values at 60 days (1.7 vs 2.6; P = .01) and 90 days (1.6 vs 2.3; P = .002; Figure 1 B) after CAR-T.

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Duffy-null patients had a lower rate of prior autologous stem cell transplant (64% vs 79%) or at least 1 high-risk cytogenetic abnormality (39% vs 53%), although these differences did not reach statistical significance.

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