Barely Significant
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Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2- Advanced Breast Cancer.

Curr Oncol · 2025 · PMC11764237 · PMID 39851968

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did not reach statistical significancep = 0.173not close (p > 0.1)
showed a trendno p-value reported
For the OS, a PR-positive status showed a trend toward reduced mortality risk compared with the PR-negative patients (HR, 0.61; 95% CI, 0.30–1.24), though this did not reach statistical significance ( p = 0.173).

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