Impact of Obesity-Associated SARS-CoV-2 Mutations on COVID-19 Severity and Clinical Outcomes.

38.41 pg/mL in non-carriers), suggesting a possible trend ( p = 0.27).

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Inflammatory Markers and Clinical Parameters The analysis of plasma inflammatory markers based on SARS-CoV-2 mutations revealed certain trends in the inflammatory response profiles, though the overall results did not reach statistical significance ( Figure 4 ).

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For inflammatory markers, the G28083T mutation was associated with decreased levels of CRP and LDH, showing a trend ( p < 0.1), whereas the C25904T mutation showed a trend toward increased IL-6 levels, which could suggest mutation-related impacts on inflammation, albeit without statistical significance.

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