Neuroprotective Effect of Melatonin Loaded in Human Serum Albumin Nanoparticles Applied Subconjunctivally in a Retinal Degeneration Animal Model.

Pharmaceutics · 2025 · PMC11769568 · PMID 39861733

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

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a clear trendp < 0.05actually significant

Although there is a clear trend towards increased cell viability in all cases, only Np-HSA-Mel showed statistically significant differences (non-parametric statistics, Kruskal–Wallis test, p < 0.05) compared to RDM, indicating that this kind of treatment may have a neuroprotective effect at the retinal level.

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a strong trendno p-value reported

In addition, Np-HSA shows a strong trend towards increased cell viability in the population studied.

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