Except for CRP, no significant differences were observed, although the group with higher neutropenia tended to show better OS across each cutoff, although the difference did not reach statistical significance.
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Relationship between neutropenia caused by nanoliposomal irinotecan/fluorouracil/leucovorin and treatment outcomes in the NAPOLEON-2 study (NN-2301).
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The sentences
OS and PFS OS analysis showed that the group with higher neutropenic grades at cutoffs A and B had significantly better OS, whereas the group with higher neutropenic grades at cutoff C showed a trend towards better OS, although the difference was not statistically significant (Fig. 2 A-C).