Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD.

Summarizing the BM AML cell engraftment relative to PBS-treated mice across the three PDX models showed a trend towards reduced AML levels was observed in the PBMC + DNT group compared to the PBMC + PBS group, although the difference did not reach statistical significance ( p = 0.0645) (Figure S3B), potentially due to the limited sample size, variability among patient samples, and the potent anti-leukemic activity mediated by PBMCs alone.

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