Brain and Serum Membrane Vesicle (Exosome) Profiles in Experimental Alcohol-Related Brain Degeneration: Forging the Path to Non-Invasive Liquid Biopsy Diagnostics.

J Mol Pathol (Basel) · 2024 · PMC11810071 · PMID 39931524

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hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

The 8-OHdG nucleic acid damage marker was expressed at significantly lower levels in the ethanol-exposed TL-Tx ( p = 0.0074; Figure 7D ), showed a trend-wise increase in the TL-MVs ( p = 0.08; Figure 7E ) from the ethanol-exposed animals, and was unaltered by ethanol in the S-EVs ( Figure 7F ). 3.5.

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did not reach statistical significanceno p-value reported

Although the S-EV GFAP levels were also lower in the ethanol samples, the response did not reach statistical significance.

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