A related HLA-DR - CD38 + cluster (cluster 3) was not significantly different ( P = .2771) but showed a trend towards a higher frequency in the CD-associated fistula compared with the cryptoglandular.
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Activated HLA-DR+CD38+ Effector Th1/17 Cells Distinguish Crohn's Disease-associated Perianal Fistulas from Cryptoglandular Fistulas.
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The sentences
These features were shared to a lesser extent with HLA-DR + CD38 - CD4 + T EM but did not reach statistical significance ( Supplementary Figure 7A - F ).