Small molecule treatment alleviates photoreceptor cilia defects in LCA5-deficient human retinal organoids.

Acta Neuropathol Commun · 2025 · PMC11817871 · PMID 39934925

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showed a trendno p-value reported

Moreover, all treatments showed a trend in increasing OS length.

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did not reach statistical significanceno p-value reported

Quantification of the cilia incidence showed a reduction in the cilia number in LCA5-deficient organoids, but it did not reach statistical significance, suggesting no major ciliation defects (Supplementary Fig.

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