Home cage-based insights into motor learning and strategy adaptation in a Huntington disease mouse model.

A trend was noted towards greater variability in zQ175 mice, taking them longer to adapt their performance, although this did not reach statistical significance.

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Statistical analysis via two-way ANOVA revealed that the interaction of genotype and day was highly significant ( Fig 3D ), indicating a behavioral shift in zQ175 mice over time toward increased entrance frequency.

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This absence of a clear trend in zQ175 mice, particularly in the face of success, implies a deficit in reward-modulated behavioral adjustment.

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