Barely Significant
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Serum uric acid/creatinine ratio and 1-year stroke recurrence in patient with acute ischemic stroke and abnormal renal function: results from the Xi'an stroke registry study of China.

Front Neurol · 2025 · PMC11832382 · PMID 39968452

2
hedged sentences
0.0100
closest p · 0.2× alpha
0.0100
boldest claim

The sentences

a significant trendP = 0.01actually significant
Compared to Q1, the Q2 and Q4 groups showed significantly reduced risk in 1-year stroke recurrence (Q2: HR = 0.46, 95% CI 0.27 to 0.79, P = 0.005; Q4: HR = 0.47, 95% CI 0.27 to 0.81, P = 0.007), with a significant trend across all quartiles ( P = 0.01 for trend tests).

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They also observed a trend suggesting a protective effect of SUA/SCr in patients with abnormal renal function (eGFR < 90 ml/min/1.73 m 2 ), although the association did not reach statistical significance ( 31 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.