COVID-19 patients also more frequently presented the homozygous FcγRIIa R131 variant, although this did not reach statistical significance.
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FcγRIIa-mediated antibody-dependent uptake of SARS-CoV-2 enhances IL-6 expression of monocytes.
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The sentences
Results showed a trend towards higher frequency of homozygosity of the rs1801274 G allele encoding R/R at amino acid 131 among COVID-19 patients (37.5%) than among healthy blood donors (22.2%; χ 2 P = 0.14; Fig. 6 ).