Long-Term IGF-1 Maintenance in the Upper-Normal Range Has Beneficial Effect on Low-Grade Inflammation Marker in Adults with Growth Hormone Deficiency.

Int J Mol Sci · 2025 · PMC11900236 · PMID 40076636

Europe PMC DOI

hedged sentences

0.0360

closest p · 0.7× alpha

0.1410

boldest claim

The sentences

nominally significantp = 0.036actually significant

Furthermore, a positive correlation between the 5-year mean IGF-1 SDS and the duration of GHRT was nominally significant (r = 0.421, p = 0.036).

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did not reach statistical significancep = 0.141not close (p > 0.1)

A trend of negative correlation between the mean IGF-1 SDS and body fat percentage was also observed over the 5-year period but did not reach statistical significance (r = −0.291, p = 0.141).

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