Barely Significant
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Cranial radiation disrupts dopaminergic signaling and connectivity in the mammalian brain.

Acta Neuropathol Commun · 2025 · PMC11905640 · PMID 40083022

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showed a trendno p-value reported
Although PFC-VTA coherence also showed a trend toward a slow decrease by 4 weeks after irradiation in sham controls, the depression in the Delta and Theta bands persisted, suggesting a lasting alteration in the functional connectivity between the VTA and PFC within the mesocortical network (Fig. 6 D-G).

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Although there was also a trend toward a decrease in the total number of arm entries in this group, this difference did not reach statistical significance (Fig. 5 D).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.