Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.

However, exploratory post-hoc comparisons between study visits showed significant or near-significant differences between GSRS-IBS scores between study visits at baseline or before stimulation versus those conducted at the 9 or 12 month follow-ups (see Figure 1 ).

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The conducted post-hoc comparisons between study visits showed highly significant differences in Y-BOCS scores between study visits at baseline or before stimulation versus all subsequent study visits (see Figure 2 ), since Y-BOCS scores dropped considerably with optimization of the deep brain stimulation.

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We found moderate-to-large correlations between scores in the Y-BOCS and the GSRS-IBS at the 9 month and 12 month follow-up visits (see Table 3 ), albeit these associations did not reach statistical significance which may be due to the small sample size.

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