Among the genetic variants that were analyzed, TA and AA genotypes of rs2900478 in SLCO1B1 exhibited a trend toward an increased risk of endometrial cancer (OR = 1.196, 95% CI: 0.9742–1.4694, p = 0.087), but the association did not reach statistical significance.
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Genetic Variations in CYP19A1 and SLCO1B1 Genes and Their Association with Endometrial Cancer Risk in the Taiwanese Population: A Case-Control Study.
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In contrast, rs2900478 with TA and AA genotypes did not show a significant trend in this analysis.
The AG/GG genotypes of rs17601876 showed a protective effect (OR = 0.743, p = 0.006), while the TA/AA genotypes of rs2900478 exhibited a nonsignificant trend toward an increased risk.