Evaluation of pituitary tumor volume as a prognostic factor in acromegaly: A cross-sectional study in two centers.

World J Radiol · 2025 · PMC11959620 · PMID 40176958

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showed a trendno p-value reported

In this study, PitNET volume was associated with the need for higher-line therapy and showed a trend toward larger volumes in uncontrolled patients, suggesting that adenoma volume could be an additional prognostic factor in acromegaly.

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did not reach statistical significanceno p-value reported

There was a higher percentage of IGF-1 elevation at diagnosis in patients with macroadenomas and a trend towards less disease control in patients with macroadenomas (45%) compared to microadenomas (40%); however, this trend did not reach statistical significance, likely due to the small sample size.

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