Comparative evaluation of Allplex HPV28 and Anyplex II HPV28 assays for high-risk HPV genotyping in cervical samples.

PLoS One · 2025 · PMC11960881 · PMID 40168371

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closest p · 1.4× alpha

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boldest claim

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showed a trendp = 0.07so close (0.05 < p ≤ 0.1)

Conversely, the Anyplex TM II HPV28 assay showed a trend toward higher detection of HPV31 (5 cases detected only with the Anyplex TM II HPV28 versus 0 cases detected with the Allplex TM HPV28, p = 0.07) and HPV39 (7 cases detected only with the Anyplex TM II HPV28 versus 1 case detected only with the Allplex TM HPV28, p = 0.08).

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did not reach statistical significanceno p-value reported

In our study, we observed a trend toward higher detection of HPV51 and HPV52 with the Allplex TM HPV28 assay compared to the Anyplex TM II HPV28 assay (using the absolute cut-off of Ct ≤ 43 for all targeted HPV genotypes), although this difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.