Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis.

Agencia Nacional de Investigación y Desarrollo 10.13039/501100020884 11190426 Scleroderma Clinical Trials Consortium VEGF , Ang‐1, and Ang‐2 measurement VEGF plasma levels were numerically lower in patients with SSc with calcinosis than in patients with SSc without calcinosis and in healthy individuals; however, this did not reach statistical significance (patients with SSc‐calcinosis, mean ± SD 28.7 ± 22 pg/mL vs healthy control group, mean ± SD 61.1 ± 73.2 pg/mL vs patients with SSC without calcinosis, mean ± SD 80.93 ± 137 pg/mL; P = 0.440).

also in 111,027 other papers

Markers of bone resorption did not differ significantly between the groups, but OPG levels showed a trend toward higher values in patients with calcinosis and the severity of calcinosis positively correlated with both RANKL levels and the RANKL/OPG ratio.

also in 53,322 other papers