Grading systems and perineural invasion in oral squamous cell carcinoma - a disease-specific survival analysis.

Med Oral Patol Oral Cir Bucal · 2025 · PMC11972651 · PMID 39864090

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did not reach statistical significanceno p-value reported

While we aimed to align with Brandwein-Gensler’s findings, the inherent differences in the patient populations, histopathological analysis and treatment protocols could explain why our results did not reach statistical significance in other variables in the multivariate analysis.

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tendency towards significanceno p-value reported

When considering the histologic risk assessment described by Brandwein-Gensler in 2005, we found an association with tumor size (P-value: ≤0.001) and clinical stage (P-value: ≤0.001), and a tendency towards significance in lymph node metastasis (P-value: 0.05).

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